About The Founder

Aungelique O’Regan is a qualified advanced aesthetic practitioner with a passion for helping people achieve their personal goals. Her previous experience over the years including ventures into dental nursing and health and wellness has led her to the launch of Bare Brilliance, an aesthetic non-surgical cosmetic practice.



Under-Eye Anti-Ageing

Available in Windsor and Chiswick

Nucleofill is an innovative biotechnology in aesthetic medicine and anti-aging treatments. This scientifically proven method of skin biostimulation contains polynucleotides that stimulate the skin to rebuild in a three-way mechanism. Nucleofill Eyes contains highly purified Polynucleotide matrix able to activate processes of bio-regeneration in the skin both at a deep level and in the dermis. Nucleofill Eyes is a gel composed of fragments of low molecular weight polynucleotide chains. The high-density but low molecular weight structure allows a fast penetration in tissues and effective stimulation.

Nucleofill Eyes is specifically designed to improve:


• Puffiness / Bags under eyes
• Periocular wrinkles
• Regenerate the skin in the Periocular area
• Bio-restructuration of deep tissues
• Improvement of superficial wrinkles without the use of fillers
• Pre and post-surgical treatment (such as Blepharoplasty, surgical eye lift, laser).

Treatment Guidance

Our Prices

1 Session: £250
2 Sessions: £475
3 Sessions: £700

4 Sessions: £825

Before & After Nucleofill


Nucleofill Before and After


Nucleofill Before and After
What is Nucleofill?

Nucleofill is an injectable bio-remodelling regime that leverages the power of polynucleotides to stimulate collagen and elastin production in the skin to support long-lasting hydration and antioxidant supply.


Nucleofill can be used to treat multiple areas of the face, including the under-eye area. The Nucleofill Eyes treatment is specifically tailored to address the signs of ageing around the eyes, such as fine lines, wrinkles, and loss of elasticity.


Nucleofill Eyes is an innovative biotechnology that uses polynucleotides to stimulate the skin to rebuild in three ways: augmenting the production of collagen by stimulating fibroblast activity, binding with water molecules for lasting hydration within the dermal matrix and neutralising the effects of harmful free radicals.


This scientifically proven method of skin biostimulation contains fragments of low molecular weight polynucleotide chains. The high-density but low molecular weight structure allows a fast penetration in tissues and effective stimulation. The result is younger, more youthful looking skin without the use of fillers.

What Are Polynucleotides?

Polynucleotides are anti-ageing, anti-wrinkle nucleotide complexes that have been shown to help skin look and feel younger. Nucleotides are the building blocks of DNA and RNA, and they are found in all living cells. Polynucleotides are a special class of nucleotides that contain multiple nucleotides bonded together. They are found naturally in some foods, but they can also be synthesised in the laboratory. Polynucleotides have been shown to boost collagen production, increase skin elasticity, and reduce the appearance of fine lines and wrinkles. They are also a powerful antioxidant that can protect the skin from damage caused by free radicals. Polynucleotides are an exciting new anti-ageing ingredient that hold promise for helping skin look and feel its best.

How Does it Work?

Nucleofill Eyes is a unique injectable treatment that uses natural, high viscosity, high molecular weight polynucleotides to improve the appearance of the skin around the eyes. Nucleofill Eyes works in three ways: first, it strengthens and lifts the skin; second, it hydrates the skin; and third, it eliminates free radicals and protects the skin from further damage. Nucleofill Eyes is an excellent choice for those looking for a safe and effective way to improve the appearance of their skin.

Is it Safe?

Nucleofill is safe, and side effects are typically mild and temporary. The most common side effects include bruising, swelling, and redness at the injection site. Nucleofill is best used by men and women over 25 who are looking for anti-ageing treatments.


If you are considering Nucleofill Eyes to help reduce the appearance of wrinkles, it is important to consult with a qualified aesthetician or plastic surgeon who can assess your individual needs and recommend the best treatment plan for you. With the right number of Nucleofill Eyes’ sessions, you can achieve smooth, youthful-looking skin that will help you feel confident and beautiful.

How Long Does the Effects of Nucleofill Last?

Nucleofill Eyes is a minimally invasive procedure that can be used to refresh the appearance of the eyes quickly and effectively. Patients can expect to see a noticeable difference in the appearance of their eyes within a month or two. However, the lifting effect of Nucleofill Eyes can last for up to 18 months. After this time, patients may need to repeat the treatment to maintain their results.

When Will I See Results?

Nucleofill Eyes is a new type of cosmetic treatment that is said to provide excellent results in just a few sessions. But when will you see the desired results?


The timing of results depends on several factors, including the severity of your wrinkles, the area being treated, and your skin type. In general, most people can expect to see visible results between 30-60 days.

What Kinds of Results Can I Expect?

Nucleofill Eyes works to deliver three types of effects in the Cutaneous Membrane (epidermis, dermis, and subcutaneous tissue):


  • Effect in the dermo-epidermal layer: This effect is responsible for the improvement in the appearance of wrinkles and fine lines.


  • Effect at the vascular level: This effect helps improve blood circulation, which in turn helps improve skin complexion and reduce puffiness and dark circles under the eyes.


  • Effect at the level of deep tissues: This effect helps to improve the overall health of the skin, including its texture, elasticity, and firmness.


Nucleofill Eyes is a product specifically designed to improve the appearance of puffiness and bags under the eyes, periocular wrinkles, and regeneration of skin in the periocular area. Additionally, it is also meant to improve superficial wrinkles without the use of fillers and can be used as a pre- and post-surgical treatment.

How Many Sessions Do I Need of Nucleofill Eyes to Get Results?

Nucleofill treatments are provided in a series of three to four treatments, with an interval of two-four weeks between each treatment. A minimum of two sessions is recommended to see results.


Nucleofill treatments have a quick turnaround time--the treatment itself only takes 30 minutes, and there is no downtime. You can immediately return to work or your normal activities after the treatment.


Nucleofill is a minimally invasive procedure that leverages the bio-stimulating effects of polynucleotides to improve the appearance of under-eye hollows, fine lines, and wrinkles. The result is a more youthful and rested appearance.

Is Nucleofill Treatment Painful?

Nucleofill treatment is not painful. Topical anaesthetic cream is applied to numb the treatment area, reducing any discomfort from the injection.


Some patients might experience some mild discomfort/unease depending on how they tolerate fine injections. The injections cause a quick sting, and possible swelling and mild soreness near the injection sites for one to three days.


In general, patients report that the overall treatment experience is quite tolerable with minimal discomfort. Treatment sessions are typically quick and easy and recovery times are also short, with most patients feeling back to their normal selves promptly after treatment.

How Does Nucleofill Differ from Fillers?

There are many different types of fillers available today, each with their own unique benefits. However, unlike regular fillers, Nucleofill uses polynucleotides to stimulate the production of collagen and other growth factors in your skin. This helps to restore the volume and firmness of your skin, leaving it looking rejuvenated and youthful.


Aside from its anti-ageing effects, Nucleofill is also very effective at treating other skin conditions, such as acne scars or surgical scars. The treatment uses a combination of polynucleotide injections with microneedling to stimulate the production of new skin cells, which helps to heal and repair the damaged tissue underneath.

Is There Anyone Who Shouldn’t Have Nucleofill Treatment?

The treatment is not recommended for pregnant or breastfeeding women, as it is not yet known whether it is safe for them. In addition, treatment should not be performed on anyone with an active herpes infection, as this could lead to the spread of the virus. Finally, the procedure is also contraindicated for those with neoplastic diseases, as the procedure could potentially worsen the condition.

What is the treatment like?
Nucleofill is a popular choice for those seeking to achieve a more youthful appearance. The treatment involves the injection of Nucleofill into specific areas of the face, known as Bio Aesthetic Points (BAPs). Nucleofill is made from salmon DNA-based polynucleotides that prompt fibroblasts and collagen to rebuild. This makes Nucleofill an ideal choice for those who are seeking a natural way to achieve younger-looking skin. The Nucleofill treatment regime typically involves a series of treatments, spaced two-four weeks apart. The number of treatments required will depend on the individual's skin condition and goals. However, most people will see noticeable results after just three or four treatments. Nucleofill Eyes can be used on its own or combined with other treatments for best results.
Why Choose Bare Brilliance Aesthetics for Nucleofill Treatment?

If you are looking for a reliable and experienced clinic to provide you with the Nucleofill under-eye treatment, Bare Brilliance Aesthetics should be your first choice. We have many years of experience in providing high-quality aesthetic treatments and our team of experts are passionate about helping our clients achieve their desired results. Contact us today to book a consultation in Windsor or Chiswick and find out how we can help you achieve younger-looking eyes naturally.

A safe pair of hands: my expertise

My commitment to being up to date with the very latest techniques and methods is one which has seen me attend over twenty seminars and successfully complete numerous training courses in non surgical cosmetic procedures. All of these through accredited and internationally renowned institutions. These include safe practice, basic life support and infection control.

Ensuring client safety is a number one priority. To this end I am licensed, insured and trained in complications and medical emergencies. I am also an active member of the Association of Cosmetic Practitioners of Britain.